Efferent Vagal Nerve Stimulation Protects Heart Against Ischemia-Induced Arrhythmias
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چکیده
Motonori Ando, Rajesh G. Katare, Yoshihiko Kakinuma, Dongmei Zhang, Fumiyasu Yamasaki, by Preserving Connexin43 Protein Efferent Vagal Nerve Stimulation Protects Heart Against Ischemia-Induced Arrhythmias Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 2005 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation doi: 10.1161/CIRCULATIONAHA.104.525493 2005;112:164-170; originally published online July 5, 2005; Circulation. http://circ.ahajournals.org/content/112/2/164 World Wide Web at: The online version of this article, along with updated information and services, is located on the
منابع مشابه
Efferent vagal nerve stimulation protects heart against ischemia-induced arrhythmias by preserving connexin43 protein.
BACKGROUND Myocardial ischemia (MI) leads to derangements in cellular electrical stability and the generation of lethal arrhythmias. Vagal nerve stimulation has been postulated to contribute to the antifibrillatory effect. Here, we suggest a novel mechanism for the antiarrhythmogenic properties of vagal stimulation during acute MI. METHODS AND RESULTS Under anesthesia, Wistar rats underwent 3...
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BACKGROUND Vagal nerve stimulation (VNS) has been shown to provide a protective effect against ischemia/reperfusion (I/R)-related arrhythmias by preventing the loss of Connexin43 (Cx43). Our previous studies showed that atrial epicardial ganglionated plexus stimulation (GPS) might exert a VNS-like effect on ventricular electrophysiology. OBJECTIVES To investigate whether GPS could preserve Cx...
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